49ers lead Seahawks 21-13 at halftime in Week 5 matchup

San Francisco entered the break ahead 21-13, capitalising on four turnovers that each led to a touchdown. The first score came when Brock Purdy connected with Mike Evans after Renardo Green intercepted a pass. A forced fumble by Fred Warner set up Christian McCaffrey's short run for the second touchdown. The third and fourth scores were produced when Gracen Halton recovered a ball knocked loose from George Holani in the end zone just before halftime. Seattle's only points in the first half resulted from a muffed punt that led to an Emanuel Wilson touchdown, with Jason Myers adding two field goals later.

In the third quarter, Myers converted a 49-yard field goal to cut the deficit to 12-16. Seattle also forced a second interception by Green, though a penalty followed the play. The 49ers will continue without linebacker Dre Greenlaw, who was ejected after a head-butting incident with Ernest Jones IV.

Both teams have struggled on third down, each converting only one attempt. The 49ers have logged 112 total yards compared with Seattle's 110, and each side has been efficient in the red zone. Injuries remain a factor: San Francisco is without Nick Bosa and Pro Bowl fullback Kyle Juszczyk, while Seattle lists Jalen Milroe as an emergency quarterback.