Chiefs defeat Raiders as Patriots upset Bills, 5 teams still winless after Week 4

Kansas City secured a victory over Las Vegas on Sunday, handing the Raiders their first loss of the season. The San Francisco 49ers continued their unbeaten streak, while the New England Patriots defeated the Buffalo Bills in an upset.

Dallas overcame Houston, with Dak Prescott and CeeDee Lamb connecting for the decisive touchdown with 43 seconds remaining. Prescott threw for 347 yards and two touchdowns, and Lamb recorded a career-high 17 receptions for 189 yards.

Injury updates included Saquon Barkley leaving the Los Angeles Rams game with a hamstring strain, Ja'Marr Chase being ruled out after a concussion in Jacksonville, and Lamar Jackson exiting the Tennessee Titans win due to an ankle issue, replaced by Tyler Huntley.

Three teams will enter Week 5 without a loss, while five clubs are still seeking their first win.