Moderna, Merck claim melanoma vaccine halves recurrence risk in Phase III trial

Moderna, Merck claim melanoma vaccine halves recurrence risk in Phase III trial

Moderna and Merck said their personalized mRNA melanoma vaccine, intismeran autogene, cut the risk of disease recurrence or spread in a Phase III trial of 1,137 high-risk patients, with the results unveiled at the American Society of Clinical Oncology meeting in Chicago on August 17. Earlier reports from Gizmodo and Ars Technica noted that the vaccine, given alongside Merck’s Keytruda, extended recurrence-free and distant metastasis-free survival. Yahoo Finance later observed that Moderna’s shares fell 12% in pre-market trading after a prior 177% surge on the same trial success.

Acteurs

Moderna Merck Stéphane Bancel

Lieux

American Society of Clinical Oncology meeting

Articles

24 août 2026
1 au total
Inside Moderna and Merck’s cancer vaccine triumph
Inside Moderna and Merck’s cancer vaccine triumph

STAT • 24 août 08h35

A phase III study of the mRNA-based melanoma vaccine intismeran autogene showed a statistically significant reduction in the chance of disease recurrence or spread, according to results released by Moderna and Merck.

Crédibilité 72% Manip. 8% Centre
20 août 2026
2 au total
Moderna and Merck's mRNA Melanoma Vaccine Looks Like a Game Changer
Moderna and Merck's mRNA Melanoma Vaccine Looks Like a Game Changer

Gizmodo • 20 août 16h15

A Phase 3 trial showed that adding Moderna's personalized mRNA vaccine to Merck's Keytruda immunotherapy extended recurrence-free survival in high-risk melanoma patients.

Crédibilité 72% Manip. 32% Centre
After Moderna stock surge of 177% on cancer drug breakthrough, here's what Wall Street thinks happens next
After Moderna stock surge of 177% on cancer drug breakthrough, here's what Wall Street thinks happens next

Yahoo Finance • 20 août 09h10

Moderna's stock fell 12% in pre-market trading following a 177% jump on news that its mRNA melanoma vaccine met primary endpoints in a Phase 3 trial, prompting mixed reactions from analysts.

Crédibilité 72% Manip. 9% Centre
19 août 2026
2 au total
mRNA cancer vaccine succeeded in Phase 3 melanoma trial, Moderna and Merck say
mRNA cancer vaccine succeeded in Phase 3 melanoma trial, Moderna and Merck say

Ars Technica • 19 août 16h53

A late-stage study of 1,137 melanoma patients showed that a personalized mRNA vaccine combined with Keytruda extended recurrence-free and distant metastasis-free survival, according to Moderna and Merck.

Crédibilité 78% Manip. 12% Centre
Merck and Moderna say cancer vaccine shows promise in preventing recurrence of melanoma
Merck and Moderna say cancer vaccine shows promise in preventing recurrence of melanoma

NBC News • 19 août 14h37

An mRNA-based personalized vaccine combined with Merck's Keytruda showed interim evidence of extending disease-free time for high-risk melanoma patients, according to a company release.

Crédibilité 68% Manip. 12% Centre