CBS Sports analysts project outcomes for Week 5 NFL matchups
CBS Sports writers Jordan Dajani and Jared Dubin offered game picks and spread predictions for eight Week 5 NFL contests, highlighting key injuries and recent performance trends.
Week 5 of the 2026 NFL season features several high-profile games, including a London showdown between the Philadelphia Eagles and Jacksonville Jaguars and a Monday Night Football clash between the Buffalo Bills and Los Angeles Rams. CBS Sports analysts Jordan Dajani and Jared Dubin provided their selections, using odds from DraftKings Sportsbook as of Oct. 6.
Dajani favored the Dallas Cowboys to cover an 8.5-point spread against the Tampa Bay Buccaneers, citing the Cowboys' 30-point-per-game offense and questioning the Buccaneers' ability to keep pace. Dubin agreed, emphasizing the Cowboys' offensive firepower and the Buccaneers' struggling offensive line.
For the London game, Dajani picked the Jaguars to win by seven points, pointing to the Eagles' recent injuries on the offensive line and at skill positions, as well as Jacksonville's strong run defense. Dubin expected a closer contest, predicting the Eagles to stay within seven points despite their challenges.
In the Packers-Bears matchup, Dajani backed Green Bay, noting the Packers' 6-1 record against the Bears at home, while Dubin saw an opportunity for Chicago to pull off a win with quarterback Tyson Bagent.
The Steelers were favored by Dubin to beat the Colts, though Dajani highlighted the Steelers' home-field advantage and the Colts' defensive struggles. For the 49ers-Seahawks game, Dajani projected an upset by San Francisco, referencing Brock Purdy's efficiency and the 49ers' recent road success, whereas Dubin gave the edge to Seattle, citing defensive concerns for the 49ers.
Dajani predicted a Falcons victory over the Ravens, citing Michael Penix Jr.'s comfort and Bijan Robinson's production, while Dubin warned that the pick assumed Lamar Jackson would be absent for Baltimore. Finally, Dajani took the Bills as underdogs against the Rams, highlighting Buffalo's league-leading scoring average and recent ATS performance, while Dubin’s commentary focused on the Rams' inconsistent play.
Overall, the analysts underscored the impact of injuries, recent form, and historical matchups in shaping their Week 5 forecasts.