Week 4 NFL injury updates affect several fantasy starters
In Week 4 of the 2026 NFL season, multiple quarterbacks, running backs and receivers suffered injuries, prompting fantasy managers to consider waiver-wire replacements.
Several key players entered the injury list ahead of Week 4, creating challenges for fantasy football owners. Quarterbacks Caleb Williams (hamstring), Jayden Daniels (elbow) and Jaxson Dart (knee) remain sidelined, while Baker Mayfield (dislocated thumb) is expected to miss three weeks, according to head coach Todd Bowles.
Running backs De'Von Achane suffered a torn ACL that ends his season, and Breece Hall is listed as week-to-week with a quad injury. Miami will likely promote Ollie Gordon II, and New York Jets may turn to Braelon Allen if Hall misses additional time.
Wide receivers also saw setbacks: Justin Jefferson left Sunday’s game with an ankle sprain and did not practice on Wednesday, leaving his status uncertain; Puka Nacua missed two games with groin and hip issues but could return, according to team officials; Mike Evans sustained a rib strain and is listed day-to-day.
Fantasy managers are advised to monitor practice reports and consider replacements such as Jordan Addison for Jefferson, and other waiver-wire options highlighted for each position.