Bills host Lions in Thursday Night Football after opening-week victories
The Buffalo Bills will play the Detroit Lions on Thursday Night Football at Highmark Stadium, with the Bills coming off a win over the Texans and the Lions after an overtime victory over the Saints.
Buffalo and Detroit will meet on Thursday night at Highmark Stadium in Orchard Park, New York, as part of the NFL’s Week 2 Thursday Night Football schedule. The game is set to begin at 8:15 p.m. Eastern Time and will be streamed on Amazon Prime.
The Bills enter the matchup after a 36-31 win over the Houston Texans, highlighted by a late 96-yard drive that ended with a touchdown pass from quarterback Josh Allen to wide receiver Joshua Palmer with 1:36 left in regulation. Buffalo’s defense forced a second fumble by Texans quarterback C.J. Stroud.
The Lions come into the contest following an overtime victory against the New Orleans Saints. Detroit built a 21-0 lead early, but the Saints rallied to tie the game and force overtime. The Lions scored first in the extra period, and the Saints answered with a touchdown but missed a two-point conversion, allowing Detroit to secure the win.
Both teams will look to build on their opening performances as they face each other in the second week of the 2026 season.