NFL Week 6 betting picks and odds highlighted by expert handicappers
Handicappers share their top bets for Week 6 matchups, including tight end Brenton Strange, Pat Freiermuth, and the Rams versus Cardinals, with odds and suggested wagers.
Week 6 of the NFL season opened with a Denver Broncos 17-14 overtime win over the Seattle Seahawks, after the Broncos surrendered an 11-point fourth-quarter lead but secured the victory with two Sam Darnold interceptions.
The league’s handicapping team—Corbie Craig, Michael Fiddle, Matt Jacob, Jeremy Pond and Matt Russell—provided their recommended wagers for the weekend’s games.
In London, the Houston Texans host the Jacksonville Jaguars. Pond highlighted tight end Brenton Strange, noting his recent surge to 14 catches for 163 yards in the Jaguars’ last two wins and a 26.2% target share. He suggested betting on Strange to score a touchdown (+330) or achieve 5+ receptions (+136) and 6+ receptions (+265).
For the New York Jets at the New England Patriots, Russell praised quarterback Drake Maye’s scrambling ability and deep-ball accuracy, while noting the Jets’ offensive line injuries and the Patriots’ strong pass rush. He recommended taking the Jets +7.5 spread at -115.
Pond warned that the Pittsburgh Steelers face a depleted receiving corps, recommending tight end Pat Freiermuth, who has become Aaron Rodgers’ preferred red-zone target. Suggested bets include Freiermuth to score a touchdown (+320) and to exceed 3.5 receptions (+116).
Jacob discussed the Los Angeles Rams’ challenging schedule and their upcoming home game against the Arizona Cardinals, who have struggled with a 1-9 straight-up record. He advised betting on the Rams to cover the -12.5 spread at -108.
Fiddle focused on the Kansas City Chiefs versus the Los Angeles Chargers, noting that Kenneth Walker III has been the Chiefs’ primary rusher. He expects a reduced workload for Walker and suggested betting the under on his rushing attempts (19.5) at -115.
Jacob also examined the Dallas Cowboys at the Green Bay Packers, citing historical high-scoring outcomes but forecasting a lower total due to strong winds that could limit deep passes. He recommended the under for the game’s total points.