Prisco predicts Browns upset Panthers and Giants rally behind Winston in Week 3

Analyst Pete Prisco released his Week 3 NFL game predictions, noting that his straight-up record this season stands at 21-11 while his against-the-spread performance is 15-17. He said a win for the Cleveland Browns over the Carolina Panthers and a victory for the New York Giants with Jameis Winston at quarterback could help him recover from a recent losing streak.

Prisco favored the Green Bay Packers to beat the Atlanta Falcons, projecting a 27-17 result, and predicted a 32-23 win for the Buffalo Bills over the Los Angeles Chargers. He backed the Browns to upset the Panthers 23-20, citing the Browns' strong home defense.

For the Detroit Lions versus New York Jets, he selected a 28-23 Lions win, while expecting the Houston Texans to defeat the Indianapolis Colts 31-20. He projected a dominant 28-10 victory for the Kansas City Chiefs against the Miami Dolphins.

"The Giants will rally around Jameis Winston in Dart's absence," Prisco wrote regarding the Titans-Giants matchup, predicting a 23-14 Giants win.

He also chose the Cincinnati Bengals to beat the Pittsburgh Steelers 23-13, the Seattle Seahawks to defeat the Washington Commanders 24-13, and the Jacksonville Jaguars to edge the New England Patriots 21-16. The San Francisco 49ers were favored over the Arizona Cardinals, with a projected 30-17 score.

Prisco expected the Tampa Bay Buccaneers to win a close game against the Minnesota Vikings, 21-20, and predicted a high-scoring 33-30 victory for the Baltimore Ravens over the Dallas Cowboys. He favored the New Orleans Saints over the Las Vegas Raiders, the Los Angeles Rams over the Denver Broncos, and the Philadelphia Eagles over the Chicago Bears.

All picks were based on the lines listed by DraftKings and game times were given in Eastern Time.